6-Chloro-5-methyl-1-[[2-[(2-methyl-3- pyridyl)oxy]-5-pyridyl]carbamoyl]indoline (SB-242084): The First Selective and Brain Penetrant 5-HT2C Receptor Antagonist-Reference-Cited by-同舟云学术

6-Chloro-5-methyl-1-[[2-[(2-methyl-3- pyridyl)oxy]-5-pyridyl]carbamoyl]indoline (SB-242084): The First Selective and Brain Penetrant 5-HT2C Receptor Antagonist

Published:1997-10-01 Issue:22 Volume:40 Page:3494-3496
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bromidge Steven M.¹,Duckworth Malcolm¹,Forbes Ian T.¹,Ham Peter¹,King Frank D.¹,Thewlis Kevin M.¹,Blaney Frank E.¹,Naylor Christopher B.¹,Blackburn Thomas P.¹,Kennett Guy A.¹,Wood Martyn D.¹,Clarke Stephen E.¹

Affiliation:

1. SmithKline Beecham Pharmaceuticals, Discovery Research, New Frontiers Science Park, Third Avenue, Harlow, Essex, England CM19 5AW

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970424c

Reference17 articles.

1. Evidence that 5-HT2C receptor antagonists are anxiolytic in the rat Geller-Seifter model of anxiety

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