Novel Nitrogen-Enriched Oridonin Analogues with Thiazole-Fused A-Ring: Protecting Group-Free Synthesis, Enhanced Anticancer Profile, and Improved Aqueous Solubility-Reference-Cited by-同舟云学术

Novel Nitrogen-Enriched Oridonin Analogues with Thiazole-Fused A-Ring: Protecting Group-Free Synthesis, Enhanced Anticancer Profile, and Improved Aqueous Solubility

Published:2013-06-19 Issue:12 Volume:56 Page:5048-5058
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ding Chunyong¹,Zhang Yusong²³,Chen Haijun¹,Yang Zhengduo³,Wild Christopher¹,Chu Lili³,Liu Huiling¹,Shen Qiang³,Zhou Jia¹

Affiliation:

1. Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas 77555, United States

2. Department of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215004, China

3. Department of Clinical Cancer Prevention, Division of Cancer Prevention and Population Sciences, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400367n

Reference52 articles.

1. Natural Products as Leads to Potential Drugs: An Old Process or the New Hope for Drug Discovery?

2. Impact of Natural Products on Developing New Anti-Cancer Agents

3. Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

4. Natural products: An evolving role in future drug discovery

5. Discovery and Development of Natural Product-Derived Chemotherapeutic Agents Based on a Medicinal Chemistry Approach

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