Inhibition of Neuronal Nitric Oxide Synthase by 4-Amino Pteridine Derivatives: Structure−Activity Relationship of Antagonists of (6R)-5,6,7,8-Tetrahydrobiopterin Cofactor-Reference-Cited by-同舟云学术

Inhibition of Neuronal Nitric Oxide Synthase by 4-Amino Pteridine Derivatives: Structure−Activity Relationship of Antagonists of (6R)-5,6,7,8-Tetrahydrobiopterin Cofactor

Published:1999-09-18 Issue:20 Volume:42 Page:4108-4121
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Fröhlich Lothar G.¹,Kotsonis Peter¹,Traub Hermann¹,Taghavi-Moghadam Shahriyar¹,Al-Masoudi Najim¹,Hofmann Heinrich¹,Strobel Hartmut¹,Matter Hans¹,Pfleiderer Wolfgang¹,Schmidt Harald H. H. W.¹

Affiliation:

1. Department of Pharmacology and Toxicology, Julius-Maximilians University Würzburg, 97078 Würzburg, Germany, and Hoechst Marion Roussel, Research Chemistry Frankfurt, Building G 838, 65926 Frankfurt, Germany, and Faculty of Chemistry, University of Konstanz, 78434 Konstanz, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm981129a

Reference59 articles.

1. Different recombination site specificity of two developmentally regulated genome rearrangements

2. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

3. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.

Cited by 70 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design and synthesis of benzo[d]thiazol-2-yl-methyl-4-(substituted)-piperazine-1-carbothioamide as novel neuronal nitric oxide inhibitors and evaluation of their neuroprotecting effect in 6-OHDA-induced unilateral lesioned rat model of Parkinson's disease;Biomedicine & Pharmacotherapy;2022-12

2. Applications of 3-Substituted 2-Alkoxy- and 2-Alkylthiopropenals in Organic Synthesis;Mini-Reviews in Organic Chemistry;2022-03

3. Comparative routes to 7-carboxymethyl-pterin: A useful medicinal chemistry building block;Pteridines;2022-01-01

4. Soft nanocarriers for new poorly soluble conjugate of pteridine and benzimidazole: Synthesis and cytotoxic activity against tumor cells;Journal of Molecular Liquids;2020-11

5. On the Clinical Pharmacology of Reactive Oxygen Species;Pharmacological Reviews;2020-08-28