Discovery of Potent Antagonists of the Interaction between Human Double Minute 2 and Tumor Suppressor p53-Reference-Cited by-同舟云学术

Discovery of Potent Antagonists of the Interaction between Human Double Minute 2 and Tumor Suppressor p53

Published:2000-08-01 Issue:17 Volume:43 Page:3205-3208
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

García-Echeverría Carlos¹,Chène Patrick¹,Blommers Marcel J. J.¹,Furet Pascal¹

Affiliation:

1. Oncology Research and Core Technologies, Novartis Pharma Inc., CH-4002 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990966p

Reference25 articles.

1. Loss of p53 function through mutation in the p53 gene or other genomic alterations occurs in about half of all cancer cases: Greenblatt, M. S.; Bennett, W. P.; Hollstein, M.; Harris, C. C. Mutations in the p53 Tumor Suppresor Gene: Clues to Cancer Etiology and Molecular Pathogenesis.Cancer Res.1994,54, 4855−4878.

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