Molecular Structures and Dynamics of the Stepwise Activation Mechanism of a Matrix Metalloproteinase Zymogen: Challenging the Cysteine Switch Dogma-Reference-Cited by-同舟云学术

Molecular Structures and Dynamics of the Stepwise Activation Mechanism of a Matrix Metalloproteinase Zymogen: Challenging the Cysteine Switch Dogma

Published:2007-10-12 Issue:44 Volume:129 Page:13566-13574
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Rosenblum Gabriel¹,Meroueh Samy¹,Toth Marta¹,Fisher Jed F.¹,Fridman Rafael¹,Mobashery Shahriar¹,Sagi Irit¹

Affiliation:

1. Contribution from the Department of Structural Biology, The Weizmann Institute of Science, Rehovot, 76100, Israel, Department of Chemistry and Biochemistry and Walther Cancer Research Center, University of Notre Dame, Notre Dame, Indiana, 46556, and Department of Pathology, Wayne State University, Detroit, Michigan 48202

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja073941l

Reference63 articles.

1. Towards third generation matrix metalloproteinase inhibitors for cancer therapy

2. Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies

3. Matrix metalloproteinases in angiogenesis: a moving target for therapeutic intervention

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