Structurally Constrained Hybrid Derivatives Containing Octahydrobenzo[g or f]quinoline Moieties for Dopamine D2 and D3 Receptors: Binding Characterization at D2/D3 Receptors and Elucidation of a Pharmacophore Model-Reference-Cited by-同舟云学术

Structurally Constrained Hybrid Derivatives Containing Octahydrobenzo[g or f]quinoline Moieties for Dopamine D2 and D3 Receptors: Binding Characterization at D2/D3 Receptors and Elucidation of a Pharmacophore Model

Published:2008-11-18 Issue:24 Volume:51 Page:7806-7819
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Brown Dennis A.¹,Kharkar Prashant S.¹,Parrington Ingrid¹,Reith Maarten E. A.¹,Dutta Aloke K.¹

Affiliation:

1. Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan 48202, and Department of Psychiatry, Millhauser Laboratories, New York University School of Medicine, New York, New York 10016

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8008629

Reference36 articles.

1. Dopamine receptorsâphysiological understanding to therapeutic intervention potential

2. Dopamine Receptors: From Structure to Function

3. Biosynthesis, Structure, and Function of Neuromelanin and its Relation to Parkinson's Disease: A Critical Update

4. Distribution of Dopamine D3 Receptor Expressing Neurons in the Human Forebrain Comparison with D2 Receptor Expressing Neurons

5. The structural evolution of dopamine D3 receptor ligands: Structure–activity relationships and selected neuropharmacological aspects

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