Research and Development of a Second-Generation Process for Bosentan, an Endothelin Receptor Antagonist
Author:
Affiliation:
1. Roche Colorado Corporation, Boulder Technology Center, 2075 North 55th Street, Boulder, Colorado 80301, U.S.A.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op010234i
Reference11 articles.
1. Neidhart, W.; Breu, V.; Bur, D.; Burri, K.; Clozel, M.; Hirth, G.; Muller, M.; Wessel, H. P.; Ramuz, H.Chimia1996,50, 519.
2. Discovery of Ro 48-5695: A potent mixed endothelin receptor antagonist optimized from bosentan
3. Totalsynthese optisch aktiver Steroide, XV. Synthese des (+)‐1,3‐Dimethoxy‐7β‐methyl‐1,3,5(10)‐östratrien‐17‐ons
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