The Discovery of 4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic Acid (MK-2894), A Potent and Selective Prostaglandin E2 Subtype 4 Receptor Antagonist-Reference-Cited by-同舟云学术

The Discovery of 4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic Acid (MK-2894), A Potent and Selective Prostaglandin E2 Subtype 4 Receptor Antagonist

Published:2010-02-17 Issue:5 Volume:53 Page:2227-2238
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Blouin Marc¹,Han Yongxin¹,Burch Jason¹,Farand Julie¹,Mellon Christophe¹,Gaudreault Mireille²,Wrona Mark²,Lévesque Jean-François²,Denis Danielle³,Mathieu Marie-Claude³,Stocco Rino³,Vigneault Erika³,Therien Alex³,Clark Patsy⁴,Rowland Steve⁴,Xu Daigen⁴,O’Neill Gary³,Ducharme Yves¹,Friesen Rick¹

Affiliation:

1. Department of Medicinal Chemistry

2. Department of DMPK

3. Department of In Vitro Sciences

4. Department of In Vivo Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901771h

Reference35 articles.