Mass Spectrometry of RNA-Binding Proteins during Liquid–Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures-Reference-Cited by-同舟云学术

Mass Spectrometry of RNA-Binding Proteins during Liquid–Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures

Published:2023-05-05 Issue:19 Volume:145 Page:10659-10668
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Sahin Cagla¹²^ORCID,Motso Aikaterini¹,Gu Xinyu³⁴,Feyrer Hannes⁵,Lama Dilraj¹,Arndt Tina⁶^ORCID,Rising Anna⁶⁷^ORCID,Gese Genis Valentin⁸,Hällberg B. Martin⁸,Marklund Erik. G.⁹^ORCID,Schafer Nicholas P.³⁴,Petzold Katja⁵¹⁰^ORCID,Teilum Kaare²^ORCID,Wolynes Peter G.³⁴^ORCID,Landreh Michael¹¹¹^ORCID

Affiliation:

1. Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet − Biomedicum, Solnavägen 9, 17165 Solna, Sweden

2. Structural Biology and NMR Laboratory and the Linderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Ole Maaløes vej 5, 2200 Copenhagen, Denmark

3. Center for Theoretical Biological Physics, Rice University, Houston, Texas 77005, United States

4. Department of Chemistry, Rice University, Houston, Texas 77005, United States

5. Department of Medical Biochemistry and Biophysics, Karolinska Institutet − Biomedicum, Solnavägen 9, 17165 Solna, Sweden

6. Department of Biosciences and Nutrition, Karolinska Institutet, S-141 57 Huddinge, Sweden

7. Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Box 7011, S-750 07 Uppsala, Sweden

8. Department of Cell and Molecular Biology, Karolinska Institutet − Biomedicum, Solnavägen 9, 171 65 Stockholm, Sweden

9. Department of Chemistry - BMC, Uppsala University, Box 576, 751 23 Uppsala, Sweden

10. Department of Medical Biochemistry and Microbiology, Uppsala University, 751 24 Uppsala, Sweden

11. Department of Cell- and Molecular Biology, Uppsala University, Box 596, 751 24 Uppsala, Sweden

Funder

Vetenskapsrådet

Knut och Alice Wallenbergs Stiftelse

Novo Nordisk Fonden

Stiftelsen för Strategisk Forskning

Horizon 2020 Framework Programme

Cancerfonden

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.3c00932

Reference59 articles.

1. Biomolecular condensates: organizers of cellular biochemistry

2. Liquid phase condensation in cell physiology and disease

3. Widespread occurrence of the droplet state of proteins in the human proteome

4. Generic nature of the condensed states of proteins

5. Sequence grammar underlying the unfolding and phase separation of globular proteins

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phase separation in DNA double-strand break response;Nucleus;2023-12-25

2. Advances in mass spectrometry to unravel the structure and function of protein condensates;Nature Protocols;2023-10-31

3. Monitoring Disassembly and Cargo Release of Phase-Separated Peptide Coacervates with Native Mass Spectrometry;Analytical Chemistry;2023-07-13