Convergent Total Synthesis of (−)-Cyclopamine
Author:
Affiliation:
1. Department of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States
2. Research and Early Development, LEO Pharma A/S, 2750 Ballerup, Denmark
Funder
Deutscher Akademischer Austauschdienst
H2020 Marie Sklodowska-Curie Actions
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.3c09085
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1. Teratogenic compounds ofveratrum californicum (durand)—IV. First isolation of veratramine and alkaloid Q and A reliable method for isolation of cyclopamine
2. Chemistry, bioactivity and geographical diversity of steroidal alkaloids from the Liliaceae family
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4. Cyclopamine and Hedgehog Signaling: Chemistry, Biology, Medical Perspectives
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