Modular Design of Biodegradable Ionizable Lipids for Improved mRNA Delivery and Precise Cancer Metastasis Delineation In Vivo-Reference-Cited by-同舟云学术

Modular Design of Biodegradable Ionizable Lipids for Improved mRNA Delivery and Precise Cancer Metastasis Delineation In Vivo

Published:2023-10-19 Issue:44 Volume:145 Page:24302-24314
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Chen Zhaoming¹,Tian Yang¹,Yang Jieyu¹,Wu Fapu¹,Liu Senyao¹,Cao Wenwen¹,Xu Weijia¹,Hu Tao¹^ORCID,Siegwart Daniel J.²^ORCID,Xiong Hu¹^ORCID

Affiliation:

1. Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin 300071, China

2. Department of Biochemistry, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States

Funder

Nankai University

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.3c09143

Reference62 articles.

1. mRNA-based therapeutics — developing a new class of drugs

2. Tools for translation: non-viral materials for therapeutic mRNA delivery