High-Accuracy Prediction of Stabilizing Surface Mutations to the Three-Helix Bundle, UBA(1), with EmCAST-Reference-Cited by-同舟云学术

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High-Accuracy Prediction of Stabilizing Surface Mutations to the Three-Helix Bundle, UBA(1), with EmCAST

Published:2023-10-10 Issue:42 Volume:145 Page:22979-22992
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Rothfuss Michael T.¹,Becht Dustin C.¹,Zeng Baisen²,McClelland Levi J.²³,Yates-Hansen Cindee²,Bowler Bruce E.¹²^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of Montana, Missoula, Montana 59812, United States

2. Center for Biomolecular Structure and Dynamics, University of Montana, Missoula, Montana 59812, United States

3. Division of Biological Sciences, University of Montana, Missoula, Montana 59812, United States

Funder

Division of Chemistry

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.3c04966

Reference97 articles.

1. Stability of Protein Pharmaceuticals: An Update

2. Immunological mechanism underlying the immune response to recombinant human protein therapeutics

3. Stabilizing biocatalysts

4. Design of novel FN3 domains with high stability by a consensus sequence approach

5. Stabilization of a Fibronectin Type III Domain by the Removal of Unfavorable Electrostatic Interactions on the Protein Surface

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