Development of a Modeling-Based Strategy for the Safe and Effective Scale-up of Highly Energetic Hydrogenation Reactions
Author:
Affiliation:
1. Takeda Pharmaceuticals International Co., Chemical Development Laboratories-Boston, 40 Landsdowne St, Cambridge, Massachusetts 02139, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op500207r
Reference20 articles.
1. Kinetic and Calorimetric Considerations in the Scale-Up of the Catalytic Reduction of a Substituted Nitrobenzene
2. Synthesis of p-Aminophenol by Catalytic Hydrogenation of p-Nitrophenol
3. Catalytic Hydrogenation of 4-(Hydroxyamino)-2-nitrotoluene and 2,4-Nitroaminotoluene Isomers: Kinetics and Reactivity
4. Kinetics of Liquid-Phase Catalytic Hydrogenation of 4-Chloro-2-nitrophenol
5. Sun, Y.; LeBlond, C.Chemical Engineering in the Pharmaceutical Industry,1st ed.John Wiley & Sons Inc.:New York, 2011; Chapter 8, p101f.
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