Imidazole Analogues of Fluoxetine, a Novel Class of Anti-Candida Agents

Author:

Silvestri Romano1,Artico Marino1,La Regina Giuseppe1,Di Pasquali Alessandra1,De Martino Gabriella1,D'Auria Felicia Diodata1,Nencioni Lucia1,Palamara Anna Teresa1

Affiliation:

1. Istituto Pasteur - Fondazione Cenci Bolognetti, Dipartimento di Studi Farmaceutici, Università degli Studi di Roma “La Sapienza”, P.le A. Moro 5, I-00185 Roma, Italy, and Istituto di Microbiologia, Università degli Studi di Roma “La Sapienza”, P.le A. Moro 5, I-00185 Roma, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference11 articles.

1. Weinberg, E. D. Antifungal Agents.Burger's Medicinal Chemistry and DrugDiscovery, 5th ed.; Wiley-Interscience:  New York 1996; Vol. 2, pp 637−652.

2. In vitroevaluation of voriconazole against clinical isolates of yeasts, moulds and dermatophytes in comparison with itraconazole, ketoconazole, amphotericin B and griseofulvin

3. Antifungals: mechanism of action and resistance, established and novel drugs

4. Sheehan, D. J.; Hitchcock, C. A.; Silbey, C. M. Current and emerging azole antifungal agents.Clin. Microbiol. Rev1999,12, 501−517. (b) Watkins, W. J.; Renau, T. E. Progress with antifungal agents and approaches to combat fungal resistance. InAnnual Reports in Medicinal Chemistry; Doherty, A. M., Ed., Academic Press:  New York, 1999; Vol. 35, pp 157−166.

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