Structure-Based Design of Novel Class II c-Met Inhibitors: 1. Identification of Pyrazolone-Based Derivatives-Reference-Cited by-同舟云学术

Structure-Based Design of Novel Class II c-Met Inhibitors: 1. Identification of Pyrazolone-Based Derivatives

Published:2012-02-24 Issue:5 Volume:55 Page:1858-1867
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Norman Mark H.,Liu Longbin,Lee Matthew,Xi Ning,Fellows Ingrid,D’Angelo Noel D.,Dominguez Celia,Rex Karen,Bellon Steven F.¹,Kim Tae-Seong,Dussault Isabelle

Affiliation:

1. Department of Molecular Structure, Amgen Inc., 360 Binney Street, Cambridge, Massachusetts 02142, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201330u

Reference25 articles.

1. Inhibitors targeting hepatocyte growth factor receptor and their potential therapeutic applications

2. Met, metastasis, motility and more

3. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

4. From Concept to Reality: The Long Road to c-Met and RON Receptor Tyrosine Kinase Inhibitors for the Treatment of Cancer

5. Rational design of inhibitors that bind to inactive kinase conformations

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