Synthesis and Biological Evaluation of N,N′-Squaramides with High in Vivo Efficacy and Low Toxicity: Toward a Low-Cost Drug against Chagas Disease-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of N,N′-Squaramides with High in Vivo Efficacy and Low Toxicity: Toward a Low-Cost Drug against Chagas Disease

Published:2014-01-22 Issue:3 Volume:57 Page:987-999
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Olmo Francisco¹,Rotger Carmen²,Ramírez-Macías Inmaculada¹,Martínez Luis²,Marín Clotilde¹,Carreras Lucas²,Urbanová Kristína¹,Vega Manel²,Chaves-Lemaur Guillermo¹,Sampedro Angel²,Rosales María Jose¹,Sánchez-Moreno Manuel¹,Costa Antonio²

Affiliation:

1. Departamento de Parasitología, Facultad de Ciencias, Universidad de Granada, E-18071 Granada, Spain

2. Departamento de Química, Facultad de Ciencias, Universidad de las Islas Baleares, E-07122 Palma de Mallorca, Baleares, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm4017015

Reference49 articles.

1. Neglected Tropical Diseases: Multi-Target-Directed Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania

2. Innovative Lead Compounds and Formulation Strategies As Newer Kinetoplastid Therapies