Crystal Structure of the IMP-1 Metallo β-Lactamase from Pseudomonas aeruginosa and Its Complex with a Mercaptocarboxylate Inhibitor: Binding Determinants of a Potent, Broad-Spectrum Inhibitor,-Reference-Cited by-同舟云学术

Crystal Structure of the IMP-1 Metallo β-Lactamase from Pseudomonas aeruginosa and Its Complex with a Mercaptocarboxylate Inhibitor: Binding Determinants of a Potent, Broad-Spectrum Inhibitor,

Published:2000-03-25 Issue:15 Volume:39 Page:4288-4298
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Concha Néstor O.¹,Janson Cheryl A.¹,Rowling Pam¹,Pearson Stewart¹,Cheever Christy A.¹,Clarke Brian P.¹,Lewis Ceri¹,Galleni Moreno¹,Frère Jean-Marie¹,Payne David J.¹,Bateson John H.¹,Abdel-Meguid Sherin S.¹

Affiliation:

1. Departments of Structural Biology, Protein Biochemistry, Anti-Infectives, and Medicinal Chemistry, SmithKline Beecham Pharmaceuticals, 709 Swedeland Road, King of Prussia, Pennsylvania 19406, and Laboratoire d'Enzymologie & Centre d'Ingénierie des Protéines, Institut de Chimie, B6 Sart Tilman, Université de Liège, B-4000 Liège, Belgium

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi992569m

Reference77 articles.

1. The Challenges of Emerging Infectious Diseases

2. Metallo-β-lactamases— new therapeutic challenge

Cited by 302 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem;Antimicrobial Agents and Chemotherapy;2024-08-07

2. Metallo-β-lactamase inhibitors: A continuing challenge for combating antibiotic resistance;Biophysical Chemistry;2024-06

3. Lippia graveolens Essential Oil to Enhance the Effect of Imipenem against Axenic and Co-Cultures of Pseudomonas aeruginosa and Acinetobacter baumannii;Antibiotics;2024-05-14

4. Structural role of K224 in taniborbactam inhibition of NDM-1;Antimicrobial Agents and Chemotherapy;2024-02-07

5. Prediction of Phytochemicals for Their Potential to Inhibit New Delhi Metallo β-Lactamase (NDM-1);Pharmaceuticals;2023-10-03