In Silico Assay for Assessing Phospholipidosis Potential of Small Druglike Molecules: Training, Validation, and Refinement Using Several Data Sets-Reference-Cited by-同舟云学术

In Silico Assay for Assessing Phospholipidosis Potential of Small Druglike Molecules: Training, Validation, and Refinement Using Several Data Sets

Published:2012-01-04 Issue:1 Volume:55 Page:126-139
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Fischer Holger¹,Atzpodien Elke-Astrid¹,Csato Miklos¹,Doessegger Lucette¹,Lenz Barbara¹,Schmitt Georg¹,Singer Thomas¹

Affiliation:

1. Clinical Safety/Licensing and Early Development, ‡Toxicology and Pathology, §Early and Investigative Safety, Non-Clinical Safety, and ∥Non-Clinical Safety, F. Hoffmann-La Roche Ltd., CH-4070 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201082a

Reference51 articles.

1. Obstacles and Opportunities in New Drug Development

2. Can the pharmaceutical industry reduce attrition rates?

3. Drug-Induced Phospholipidosis: Are There Functional Consequences?

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