The observed inhibitory potency of 3'-azido-3'-deoxythymidine 5'-triphosphate for HIV-1 reverse transcriptase depends on the length of the poly(rA) region of the template-Reference-Cited by-同舟云学术

The observed inhibitory potency of 3'-azido-3'-deoxythymidine 5'-triphosphate for HIV-1 reverse transcriptase depends on the length of the poly(rA) region of the template

Published:1992-02-11 Issue:5 Volume:31 Page:1375-1379
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Ma Qi Feng,Bathurst Ian C.,Barr Philip J.,Kenyon George L.

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi00120a013

Reference21 articles.

1. Characterization of the human immunodeficiency virus type-1 reverse transcriptase enzyme produced in yeast

2. Inactivation of DNA polymerase I (Klenow fragment) by adenosine 2',3'-epoxide 5'-triphosphate: evidence for the formation of a tight-binding inhibitor

3. Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs.

4. Phosphorylation of 3'-azido-2',3'-dideoxyuridine and preferential inhibition of human and simian immunodeficiency virus reverse transcriptases by its 5'-triphosphate

5. The Efficacy of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex

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