Mechanism of Thioredoxin-Catalyzed Disulfide Reduction. Activation of the Buried Thiol and Role of the Variable Active-Site Residues-Reference-Cited by-同舟云学术

Mechanism of Thioredoxin-Catalyzed Disulfide Reduction. Activation of the Buried Thiol and Role of the Variable Active-Site Residues

Published:2008-02-01 Issue:8 Volume:112 Page:2511-2523
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Carvalho Alexandra T. P.¹,Swart Marcel¹,van Stralen Joost N. P.¹,Fernandes Pedro A.¹,Ramos Maria J.¹,Bickelhaupt F. Matthias¹

Affiliation:

1. REQUIMTE, Departamento de Química, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 687, P-4169-007 Porto, Portugal, and Theoretical Chemistry, Vrije Universiteit, De Boelelaan 1083, NL-1081 HV Amsterdam, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jp7104665

Reference48 articles.

2. Thioredoxin structure and mechanism: conformational changes on oxidation of the active-site sulfhydryls to a disulfide

3. Theoretical Study of the Unusual Protonation Properties of the Active Site Cysteines in Thioredoxin

4. Determination of the ΔpKa between the active site cysteines of thioredoxin and DsbA

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