Polyhistidine Peptide Inhibitor of the Aβ Calcium Channel Potently Blocks the Aβ-Induced Calcium Response in Cells. Theoretical Modeling Suggests a Cooperative Binding Process
Author:
Affiliation:
1. Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814
2. Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi1006833
Reference25 articles.
1. Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum.
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4. The Ability of Amyloid β-Protein [AβP (1-40)] to Form Ca2+ Channels Provides a Mechanism for Neuronal Death in Alzheimer's Disease
5. Disruption of Calcium Homeostasis in the Pathogenesis of Alzheimers Disease and Other Conformational Diseases
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