Development of a Scalable Synthesis of a Bruton’s Tyrosine Kinase Inhibitor via C–N and C–C Bond Couplings as an End Game Strategy
Author:
Affiliation:
1. Technical Sciences—Chemical Synthesis, Roche Palo Alto LLC, 3431 Hillview Avenue, Palo Alto, California 94304, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op4001077
Reference48 articles.
1. The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
2. Primary B Cell Immunodeficiencies: Comparisons and Contrasts
3. Defective B cell development and function in Btk-deficient mice
4. Severe B Cell Deficiency in Mice Lacking the Tec Kinase Family Members Tec and Btk
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