Structure–Activity Relationship of S-Trityl-l-Cysteine Analogues as Inhibitors of the Human Mitotic Kinesin Eg5-Reference-Cited by-同舟云学术

Structure–Activity Relationship of S-Trityl-l-Cysteine Analogues as Inhibitors of the Human Mitotic Kinesin Eg5

Published:2008-02-12 Issue:5 Volume:51 Page:1115-1125
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

DeBonis Salvatore¹,Skoufias Dimitrios A.¹,Indorato Rose-Laure¹,Liger François¹,Marquet Bernard¹,Laggner Christian¹,Joseph Benoît¹,Kozielski Frank¹

Affiliation:

1. Laboratoire des Moteurs Moléculaires and Laboratoire des Protéines du Cytosquelette, Institut de Biologie Structurale, 41, rue Jules Horowitz, 38027 Grenoble Cedex 01, France, Chimiothèque de l’UMR - CNRS 5246, Université de Lyon, Université Claude Bernard Lyon 1, 43, Boulevard du 11 Novembre 1918, 69622 Villeurbanne, France, Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences (CMBI), University of Innsbruck, Innrain 52c, 6020 Innsbruck, Austria, and The...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070606z

Reference43 articles.

1. Functional Analysis of Human Microtubule-based Motor Proteins, the Kinesins and Dyneins, in Mitosis/Cytokinesis Using RNA Interference

2. Past and future of the mitotic spindle as an oncology target

3. Mitotic Kinesins: Prospects for Antimitotic Drug Discovery

4. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

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