General Base Catalysis for Cleavage by the Active-Site Cytosine of the Hepatitis Delta Virus Ribozyme: QM/MM Calculations Establish Chemical Feasibility-Reference-Cited by-同舟云学术

General Base Catalysis for Cleavage by the Active-Site Cytosine of the Hepatitis Delta Virus Ribozyme: QM/MM Calculations Establish Chemical Feasibility

Published:2008-08-08 Issue:35 Volume:112 Page:11177-11187
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Banáš Pavel¹,Rulíšek Lubomír¹,Hánošová Veronika¹,Svozil Daniel¹,Walter Nils G.¹,Šponer Jiří¹,Otyepka Michal¹

Affiliation:

1. Department of Physical Chemistry and Center for Biomolecules and Complex Molecular Systems, Palacky University, tr. Svobody 26, 771 46, Olomouc, Czech Republic, Institute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 612 65 Brno, Czech Republic, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, and Center for Biomolecules and Complex Molecular Systems, Flemingovo nam. 2, 166 10, Prague 6, Czech Republic, Gilead Sciences and IOCB...

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jp802592z

Reference80 articles.

1. The catalytic diversity of RNAs

2. Ribozyme catalysis: not different, just worse

3. A Genomewide Search for Ribozymes Reveals an HDV-Like Sequence in the Human CPEB3 Gene

4. Imidazole Rescue of a Cytosine Mutation in a Self-Cleaving Ribozyme

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