A Practical Synthesis of a cis-4,5-Bis(4-chlorophenyl)imidazoline Intermediate for Nutlin Analogues-Reference-Cited by-同舟云学术

A Practical Synthesis of a cis-4,5-Bis(4-chlorophenyl)imidazoline Intermediate for Nutlin Analogues

Published:2012-10-30 Issue:11 Volume:16 Page:1866-1869
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Shu Lianhe¹,Wang Ping¹,Liu Wen¹,Gu Chen¹

Affiliation:

1. Process Research and Synthesis, Pharma Research and Early Development (pRED), Hoffmann-La Roche, Inc., 340 Kingsland Street, Nutley, New Jersey 07110, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op300254q

Reference23 articles.

1. In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2

2. Recent Advances in the Therapeutic Perspectives of Nutlin-3

3. Fotouhi, N.; Haley, G. J.; Simonsen, K. B.; Vu, B. T.; Webber, S. E.Novelcis-Imidazolines. PCT Int. Appl. WO 2005110996, November 24, 2005.

4. A retro-Diels-Alder approach to oxazoles and imidazoles

5. An efficient method for the preparation of N,N-disubstituted 1,2-diamines

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