Molecular Dynamics Simulations Reveal a Novel Mechanism for ATP Inhibition of Insulin Degrading Enzyme

Author:

da Cruz Carlos H. B.1,Seabra Gustavo1

Affiliation:

1. Departamento de Química Fundamental, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, s/n, Cidade Universitária, Recife-PE Brazil, 50.740-560

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Reference60 articles.

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2. Alzheimer’s Association. 2009: The Year in Alzheimer Science;London, 2009; p623.

3. Alzheimer’s Association. Alzheimer’s Disease Facts And Figures;London, 2012; Vol.8, p72.

4. Insulin, insulin-degrading enzyme and amyloid-β peptide in Alzheimer's disease: review and hypothesis

5. Insulin-degrading enzyme in the Alzheimer's disease brain: prominent localization in neurons and senile plaques

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