Independent Generation and Reactivity of 2‘-Deoxy-5-methyleneuridin-5-yl, a Significant Reactive Intermediate Produced from Thymidine as a Result of Oxidative Stress-Reference-Cited by-同舟云学术

Independent Generation and Reactivity of 2‘-Deoxy-5-methyleneuridin-5-yl, a Significant Reactive Intermediate Produced from Thymidine as a Result of Oxidative Stress

Published:2000-07-01 Issue:15 Volume:65 Page:4648-4654
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Anderson Aaron S.¹,Hwang Jae-Taeg¹,Greenberg Marc M.¹

Affiliation:

1. Department of Chemistry, Colorado State University Fort Collins, Colorado 80523

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo000271s

Reference46 articles.

1. Chemistry of DNA Damage

2. Oxidative Strand Scission of Nucleic Acids: Routes Initiated by Hydrogen Abstraction from the Sugar Moiety

3. Carbon—Hydrogen Bonds of DNA Sugar Units as Targets for Chemical Nucleases and Drugs

4. Oxidative Nucleobase Modifications Leading to Strand Scission

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