A Nucleotide-Analogue-Induced Gain of Function Corrects the Error-Prone Nature of Human DNA Polymerase iota-Reference-Cited by-同舟云学术

A Nucleotide-Analogue-Induced Gain of Function Corrects the Error-Prone Nature of Human DNA Polymerase iota

Published:2012-06-14 Issue:25 Volume:134 Page:10698-10705
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Ketkar Amit¹,Zafar Maroof K.¹,Banerjee Surajit²,Marquez Victor E.³,Egli Martin⁴,Eoff Robert L.¹

Affiliation:

1. Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205-7199, United States

2. Northeastern Collaborative Access Team and Department of Chemistry and Chemical Biology, Cornell University, Building 436E, Argonne National Laboratory, Argonne, Illinois 60439, United States

3. Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, Maryland 21702, United States

4. Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, United States

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja304176q

Reference51 articles.

1. Nucleic acid polymerases use a general acid for nucleotidyl transfer

2. DNA Polymerase Fidelity: Kinetics, Structure, and Checkpoints

3. Human cancers express a mutator phenotype

4. A cancer-associated DNA polymerase variant modeled in yeast causes a catastrophic increase in genomic instability

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