Modulating Lipoprotein Transcellular Transport and Atherosclerotic Plaque Formation in ApoE–/– Mice via Nanoformulated Lipid–Methotrexate Conjugates

Author:

Di Francesco Valentina12ORCID,Gurgone Danila34ORCID,Palomba Roberto1ORCID,Ferreira Miguel Filipe Moreira Marques1ORCID,Catelani Tiziano5ORCID,Cervadoro Antonio1ORCID,Maffia Pasquale346ORCID,Decuzzi Paolo1ORCID

Affiliation:

1. Laboratory of Nanotechnology for Precision Medicine, Fondazione Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy

2. Department of Informatics, Bioengineering, Robotics and System Engineering, University of Genoa, Via Opera Pia, 13, 16145 Genoa, Italy

3. Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, United Kingdom

4. Department of Pharmacy, University of Naples Federico II, Naples 80131, Italy

5. Electron Microscopy Facility, Istituto Italiano di Tecnologia, via Morego 30, Genova 16163, Italy

6. Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, United Kingdom

Funder

Engineering and Physical Sciences Research Council

British Heart Foundation

H2020 Marie Sklodowska-Curie Actions

Wellcome Trust

FP7 Ideas: European Research Council

Publisher

American Chemical Society (ACS)

Subject

General Materials Science

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