Synthesis of CDDO–Amino Acid–Nitric Oxide Donor Trihybrids as Potential Antitumor Agents against Both Drug-Sensitive and Drug-Resistant Colon Cancer-Reference-Cited by-同舟云学术

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Synthesis of CDDO–Amino Acid–Nitric Oxide Donor Trihybrids as Potential Antitumor Agents against Both Drug-Sensitive and Drug-Resistant Colon Cancer

Published:2015-02-23 Issue:5 Volume:58 Page:2452-2464
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ai Yong¹²,Kang Fenghua¹²,Huang Zhangjian¹²,Xue Xiaowen¹,Lai Yisheng¹²,Peng Sixun¹²,Tian Jide³,Zhang Yihua¹²

Affiliation:

1. State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, PR China

2. Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, China Pharmaceutical University, Nanjing 210009, PR China

3. Department of Molecular and Medical Pharmacology, University of California, Los Angeles, California 90095, United States

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5019302

Reference53 articles.

1. Multidrug resistance in cancer: role of ATP–dependent transporters

2. Targeting multidrug resistance in cancer

3. Anti-Apoptotic Mechanisms of Drug Resistance in Cancer

4. Human Multidrug Resistance ABCB and ABCG Transporters: Participation in a Chemoimmunity Defense System

5. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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