Curtailing the Hydroxylaminobarbituric Acid–Hydantoin Rearrangement To Favor HNO Generation
Author:
Affiliation:
1. Department of Chemistry, 3400 North Charles Street, Johns Hopkins University, Baltimore, Maryland 21218, United States
Funder
Division of Chemistry
Cardioxyl Pharmaceuticals
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo5023316
Reference30 articles.
1. Playing with Cardiac “Redox Switches”: The “HNO Way” to Modulate Cardiac Function
2. The Specificity of Nitroxyl Chemistry Is Unique Among Nitrogen Oxides in Biological Systems
3. Positive inotropic and lusitropic effects of HNO/NO- in failing hearts: Independence from -adrenergic signaling
4. Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling
5. Nitroxyl (HNO): A Novel Redox Signaling Molecule
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