Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors-Reference-Cited by-同舟云学术

Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors

Published:2012-03-08 Issue:6 Volume:55 Page:2894-2898
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gising Johan¹,Nilsson Mikael T.²,Odell Luke R.¹,Yahiaoui Samir¹,Lindh Martin¹,Iyer Harini³,Sinha Achyut M.³,Srinivasa Bachally R.³,Larhed Mats¹,Mowbray Sherry L.²,Karlén Anders¹

Affiliation:

1. Department of Medicinal Chemistry, Organic Pharmaceutical Chemistry, BMC, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden

2. Department of Cell and Molecular Biology, Structural Biology, BMC, Uppsala University, Box 596, SE-751 24 Uppsala, Sweden

3. AstraZeneca India Private Limited, Bellary Road, Hebbal, Bangalore 560024, India

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201212h

Reference22 articles.

1. www.who.org.

2. XDR Tuberculosis — Implications for Global Public Health

3. Resistance to second-line injectables and treatment outcomes in multidrug-resistant and extensively drug-resistant tuberculosis cases

4. Structural model for the reaction mechanism of glutamine synthetase, based on five crystal structures of enzyme-substrate complexes

5. Ammonia inhibits phagosome–lysosome fusion in macrophages

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