Post-Polyketide Synthase Steps in Iso-migrastatin Biosynthesis, Featuring Tailoring Enzymes with Broad Substrate Specificity
Author:
Affiliation:
1. Division of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin, Madison, Wisconsin 53705, United States
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja4002635
Reference37 articles.
1. Multifaceted Modes of Action for the Glutarimide-Containing Polyketides Revealed
2. Iso-Migrastatin Congeners from Streptomyces platensis and Generation of a Glutarimide Polyketide Library Featuring the Dorrigocin, Lactimidomycin, Migrastatin, and NK30424 Scaffolds
3. Migrastatin, a New Inhibitor of Tumor Cell Migration from Streptomyces sp. MK929-43F1. Taxonomy, Fermentation, Isolation and Biological Activities.
4. Migrastatin, a Novel 14-Membered Ring Macrolide, Inhibits Anchorage-independent Growth of Human Small Cell Lung Carcinoma Ms-1 Cells.
5. Migrastatin, a Novel 14-Membered Lactone from Streptomyces sp. MK929-43F1.
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