On the Histone Lysine Methyltransferase Activity of Fungal Metabolite Chaetocin

Author:

Cherblanc Fanny L.1,Chapman Kathryn L.2,Reid Jim3,Borg Aaron J.4,Sundriyal Sandeep1,Alcazar-Fuoli Laura5,Bignell Elaine5,Demetriades Marina6,Schofield Christopher J.6,DiMaggio Peter A.4,Brown Robert7,Fuchter Matthew J.1

Affiliation:

1. Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom

2. Mechanism and Functional Screening Facility, Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London W12 ONN, United Kingdom

3. Domainex Ltd., 162 Cambridge Science Park, Milton Road, Cambridge CB4 0GH, United Kingdom

4. Department of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, United Kingdom

5. Centre for Molecular Microbiology and Infection, Imperial College London, Armstrong Road, London SW7 2AZ, United Kingdom

6. Department of Chemistry and the Oxford Centre for Integrative Systems Biology, Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom

7. Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, London W12 ONN, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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