Evaluation of 18F-Labeled Benzodioxine Piperazine-Based Dopamine D4 Receptor Ligands: Lipophilicity as a Determinate of Nonspecific Binding
Author:
Affiliation:
1. Institute of Neuroscience and Medicine, INM-5, Nuclear Chemistry, Forschungszentrum Jülich GmbH, Jülich, Germany
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm200762g
Reference55 articles.
1. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine
2. Dopamine D4 versus D2 receptor selectivity of dopamine receptor antagonists: possible therapeutic implications
3. Multiple dopamine D4 receptor variants in the human population
4. The Genetic Architecture of Selection at the Human Dopamine Receptor D4 (DRD4) Gene Locus
5. Direct determination of dopamine D4 receptors in normal and schizophrenic postmortem brain tissue: a [3H]NGD-94-1 study
Cited by 27 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods;Biomolecules;2021-04-02
2. Arene Amination Instead of Fluorination: Substitution Pattern Governs the Reactivity of Dialkoxybenzenes with Selectfluor;The Journal of Organic Chemistry;2021-03-31
3. 11C- and 18F-Radiotracers for In Vivo Imaging of the Dopamine System: Past, Present and Future;Biomedicines;2021-01-22
4. Radiosynthesis and evaluation of 18F-labeled dopamine D4-receptor ligands;Nuclear Medicine and Biology;2021-01
5. PET and SPECT Imaging of the Central Dopamine System in Humans;PET and SPECT of Neurobiological Systems;2020-09-30
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3