Potent and Selective Inhibitors of CDPK1 from T. gondii and C. parvum Based on a 5-Aminopyrazole-4-carboxamide Scaffold-Reference-Cited by-同舟云学术

Potent and Selective Inhibitors of CDPK1 from T. gondii and C. parvum Based on a 5-Aminopyrazole-4-carboxamide Scaffold

Published:2013-11-20 Issue:1 Volume:5 Page:40-44
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Zhang Zhongsheng¹,Ojo Kayode K.²,Vidadala RamaSubbaRao³,Huang Wenlin¹,Geiger Jennifer A.⁴,Scheele Suzanne⁴,Choi Ryan²,Reid Molly C.²,Keyloun Katelyn R.²,Rivas Kasey²,Kallur Siddaramaiah Latha¹,Comess Kenneth M.⁵,Robinson Kenneth P.⁵,Merta Philip J.⁵,Kifle Lemma⁵,Hol Wim G. J.¹,Parsons Marilyn⁴,Merritt Ethan A.¹,Maly Dustin J.³,Verlinde Christophe L. M. J.¹,Van Voorhis Wesley C.²,Fan Erkang¹

Affiliation:

1. Department of Biochemistry, University of Washington, Seattle, Washington 98195, United States

2. Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington 98195, United States

3. Department of Chemistry, University of Washington, Seattle, Washington 98195, United States

4. Seattle Biomedical Research Institute, Seattle, Washington 98109, United States

5. High Throughput Biology, Global Pharmaceutical R&D, AbbVie, North Chicago, Illinois 60064, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml400315s

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2. Toxoplasma gondii

3. Cryptosporidium Species

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5. Closing the diarrhoea diagnostic gap in Indian children by the application of molecular techniques

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