Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)-Reference-Cited by-同舟云学术

Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

Published:2012-03-28 Issue:9 Volume:55 Page:4101-4113
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Flygare John A.,Beresini Maureen,Budha Nageshwar,Chan Helen,Chan Iris T.,Cheeti Sravanthi,Cohen Frederick,Deshayes Kurt,Doerner Karl,Eckhardt S. Gail¹,Elliott Linda O.,Feng Bainian,Franklin Matthew C.,Reisner Stacy Frankovitz,Gazzard Lewis,Halladay Jason,Hymowitz Sarah G.,La Hank,LoRusso Patricia²,Maurer Brigitte,Murray Lesley,Plise Emile,Quan Clifford,Stephan Jean-Philippe,Young Shin G.,Tom Jeffrey,Tsui Vickie,Um Joanne,Varfolomeev Eugene,Vucic Domagoj,Wagner Andrew J.³,Wallweber Heidi J. A.,Wang Lan,Ware Joseph,Wen Zhaoyang,Wong Harvey,Wong Jonathan M.,Wong Melisa,Wong Susan,Yu Ron,Zobel Kerry,Fairbrother Wayne J.

Affiliation:

1. Division of Medical Oncology, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado 80045, United States

2. Department of Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48201, United States

3. Center for Sarcoma and Bone Oncology, Dana Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300060k

Reference63 articles.

1. The inhibitors of apoptosis (IAPs) as cancer targets

2. ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

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