Targeting the Hsp90 Molecular Chaperone with Novel Macrolactams. Synthesis, Structural, Binding, and Cellular Studies-Reference-Cited by-同舟云学术

Targeting the Hsp90 Molecular Chaperone with Novel Macrolactams. Synthesis, Structural, Binding, and Cellular Studies

Published:2011-10-04 Issue:12 Volume:6 Page:1339-1347
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Day James E. H.¹,Sharp Swee Y.²,Rowlands Martin G.²,Aherne Wynne²,Hayes Angela²,Raynaud Florence I.²,Lewis William¹,Roe S. Mark³,Prodromou Chrisostomos³,Pearl Laurence H.³,Workman Paul²,Moody Christopher J.¹

Affiliation:

1. School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, U.K.

2. Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, Haddow Laboratories, 15 Cotswold Road, Sutton, Surrey SM2 5NG, U.K.

3. Section of Structural Biology, The Institute of Cancer Research, Chester Beatty Laboratories, 237 Fulham Road, London SW3 6JB, U.K.

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb200196e

Reference66 articles.

1. Chemistry and biology of resorcylic acid lactones

2. Resorcylic acid lactones: A pluripotent scaffold with therapeutic potential

3. Resorcylic acid lactones as new lead structures for kinase inhibition

4. A New Antifungal Substance of Fungal Origin

5. The constitution of radicicol

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