Computational Studies on Tetrahydropyrimidine-2-one HIV-1 Protease Inhibitors: Improving Three-Dimensional Quantitative Structure−Activity Relationship Comparative Molecular Field Analysis Models by Inclusion of Calculated Inhibitor- and Receptor-Based Properties-Reference-Cited by-同舟云学术

Computational Studies on Tetrahydropyrimidine-2-one HIV-1 Protease Inhibitors: Improving Three-Dimensional Quantitative Structure−Activity Relationship Comparative Molecular Field Analysis Models by Inclusion of Calculated Inhibitor- and Receptor-Based Properties

Published:2002-01-17 Issue:4 Volume:45 Page:973-983
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nair Anil C.¹,Jayatilleke Philippa¹,Wang Xia¹,Miertus Stanislav¹,Welsh William J.¹

Affiliation:

1. Department of Chemistry & Biochemistry and Center for Molecular Electronics, University of MissouriSt. Louis, St. Louis, Missouri 63121, and International Center for Science and High Technology, UNIDO, Area Science Park, Padriciano 99, Trieste 34012, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm010417v

Reference28 articles.

1. Molecular characterization of gag proteins from simian immunodeficiency virus (SIVMne)

2. A deletion mutation in the 5' part of the pol gene of Moloney murine leukemia virus blocks proteolytic processing of the gag and pol polyproteins

3. Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity

4. A Synthetic HIV-1 Protease Inhibitor with Antiviral Activity Arrests HIV-Like Particle Maturation

Cited by 64 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Saccharin based ionic liquid: Novel and recyclable catalyst for eco-friendly mechanosynthesis of Biginelli and Hantzcsh heterocycles under solvent-free conditions;Journal of Molecular Structure;2023-11

2. In-silico Ligand and Structure Based Design of HIV-1 Protease Inhibitors: Current Trends and Future Directions;Research Journal of Pharmacy and Technology;2022-04-23

3. Controllable methylenation with ethylene glycol as the methylene source: bridging enaminones and synthesis of tetrahydropyrimidines;Organic Chemistry Frontiers;2022

4. Formal [2+2+2] Cycloaddition Reaction of 1,3,5‐Triazinanes with diethyl acetylene dicarboxylate: Approach to Tetrahydropyrimidines;European Journal of Organic Chemistry;2021-11-15

5. Design, Green Synthesis, and Biological Evaluation of New Substituted Tetrahydropyrimidine Derivatives as Acetylcholinesterase Inhibitors;Polycyclic Aromatic Compounds;2021-06-03