Site-Directed Mutagenesis of Glutamate-166 in .beta.-Lactamase Leads to a Branched Path Mechanism
Author:
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi00190a015
Reference34 articles.
1. Site-directed mutants, at position 166, of RTEM-1 beta-lactamase that form a stable acyl-enzyme intermediate with penicillin.
2. The structure of β-lactamases
3. Sexually Transmitted Diseases in the AIDS Era
4. Trapping the acyl-enzyme intermediate in β-lactamase I catalysis
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