1. Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92037, Department of Pharmacology, Creighton University School of Medicine, Omaha, Nebraska 68178, and Facultad de Ciencias Marinas, Universidad Autonoma de Baja California, Ensenada, BC, 22830, Mexico