1. Department of Medicinal Chemistry, Institute of Pharmacy, University of Tromsø, N-9037 Tromsø, Norway; Department of Pharmaceutics, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100 Copenhagen, Denmark; Department of Chemistry, University of Tromsø, N-9037 Tromsø, Norway; and Department of Chemistry, Medicinal Chemistry, Göteborg University, SE-412 96 Göteborg, Sweden