Potent and Selective Steroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 7, an Enzyme That Catalyzes the Reduction of the Key Hormones Estrone and Dihydrotestosterone-Reference-Cited by-同舟云学术

Potent and Selective Steroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 7, an Enzyme That Catalyzes the Reduction of the Key Hormones Estrone and Dihydrotestosterone

Published:2009-09-22 Issue:23 Volume:52 Page:7488-7502
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bellavance Édith¹,Luu-The Van¹,Poirier Donald¹

Affiliation:

1. Laboratory of Medicinal Chemistry, Oncology and Molecular Endocrinology, CHUQ (CHUL) Research Center and Laval University, 2705 Boulevard Laurier, Québec G1V 4G2, Canada

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900921c

Reference50 articles.

1. Integrated view on 17beta-hydroxysteroid dehydrogenases

2. Androgen biosynthetic pathways in the human prostate

3. Structure and function of human 17β-hydroxysteroid dehydrogenases

4. Control of cell proliferation by steroids: The role of 17HSDs

5. Analysis and characteristics of multiple types of human 17β-hydroxysteroid dehydrogenase

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