Synthetic and Mechanistic Studies of (2R,3S)-3-Vinylmalic Acid as a Mechanism-Based Inhibitor of 3-Isopropylmalate Dehydrogenase-Reference-Cited by-同舟云学术

Synthetic and Mechanistic Studies of (2R,3S)-3-Vinylmalic Acid as a Mechanism-Based Inhibitor of 3-Isopropylmalate Dehydrogenase

Published:1999-08-01 Issue:17 Volume:64 Page:6159-6165
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Chiba Akira¹,Aoyama Tetsuya¹,Suzuki Rieko¹,Eguchi Tadashi¹,Oshima Tairo¹,Kakinuma Katsumi¹

Affiliation:

1. Department of Chemistry, Tokyo Institute of Technology, O-okayama, Meguro-ku, Tokyo 152-8551, Japan, and Department of Molecular Biology, Tokyo University of Pharmacy and Life Science, Hachioji-shi, Tokyo 192-0392, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo982206c

Reference30 articles.

1. Cloning of 3-Isopropylmalate Dehydrogenase Gene of an Extreme Thermophile and Partial Purification of the Gene Product

2. High guanine plus cytosine content in the third letter of codons of an extreme thermophile. DNA sequence of the isopropylmalate dehydrogenase of Thermus thermophilus.

3. Purification, Catalytic Properties, and Thermal Stability of Threo-Ds-3-Isopropylmalate Dehydrogenase Coded by leuB Gene from an Extreme Thermophile, Thermus thermophilus Strain HB81

4. A Preparative Method of DL-threo-3-Isopropylmalic Acid and DL-threo-[2-2H]-3-Isopropylmalic Acid

5. Stereospecificity of the Hydride Transfer Reaction Catalyzed by Isopropylmalate Dehydrogenase of Thermophilic BacteriaThermus thermophilus

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