Viscosity-Lowering Effect of Amino Acids and Salts on Highly Concentrated Solutions of Two IgG1 Monoclonal Antibodies-Reference-Cited by-同舟云学术

Viscosity-Lowering Effect of Amino Acids and Salts on Highly Concentrated Solutions of Two IgG1 Monoclonal Antibodies

Published:2015-11-12 Issue:12 Volume:12 Page:4478-4487
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Wang Shujing¹,Zhang Ning²,Hu Tao²,Dai Weiguo³,Feng Xiuying²,Zhang Xinyi¹,Qian Feng¹

Affiliation:

1. School of Pharmaceutical Sciences and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Tsinghua University, Beijing 100084, China

2. China R&D and Scientific Affair, Shanghai Discovery Center, Janssen Research & Development, Johnson & Johnson, Shanghai 200030, China

3. Janssen Research & Development, Johnson & Johnson, Malvern, Pennsylvania 19355, United States

Funder

Central Committee of the Communist Party of China

China Scholarship Council

Center for Life Sciences

Janssen Pharmaceuticals

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.5b00643

Reference54 articles.

1. Development trends for human monoclonal antibody therapeutics

2. Monoclonal antibodies — a proven and rapidly expanding therapeutic modality for human diseases

3. Building better monoclonal antibody-based therapeutics

4. Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

5. High Concentration Formulation Feasibility of Human Immunoglubulin G for Subcutaneous Administration

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