Usefulness of Caco-2/HT29-MTX and Caco-2/HT29-MTX/Raji B Coculture Models To Predict Intestinal and Colonic Permeability Compared to Caco-2 Monoculture

Author:

Lozoya-Agullo Isabel12,Araújo Francisca34,González-Álvarez Isabel1,Merino-Sanjuán Matilde25,González-Álvarez Marta1,Bermejo Marival1,Sarmento Bruno346ORCID

Affiliation:

1. Department of Pharmacokinetics and Pharmaceutical Technology, Miguel Hernandez University, San Juan de Alicante, 03550 Alicante, Spain

2. Department of Pharmacokinetics and Pharmaceutical Technology, University of Valencia, Av. de Blasco Ibáñez, 13, 46010 Valencia, Spain

3. i3S−Instituto de Investigação e Inovação em Saúde, University of Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal

4. INEB−Instituto de Engenharia Biomédica, University of Porto, Rua Alfredo Allen 208, 4200-135 Porto, Portugal

5. Molecular Recognition and Technological Development, Polytechnic University−University of Valencia, Camí de Vera, s/n, 46022 Valencia, Spain

6. CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Rua Central da Gandra 1317, 4585-116 Gandra, Portugal

Funder

European Commission

European Regional Development Fund

Ministerio de Educaci?n, Cultura y Deporte

Funda??o para a Ci?ncia e a Tecnologia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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