Non-uniformity of Changes in Drug-Metabolizing Enzymes and Transporters in Liver Cirrhosis: Implications for Drug Dosage Adjustment-Reference-Cited by-同舟云学术

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Non-uniformity of Changes in Drug-Metabolizing Enzymes and Transporters in Liver Cirrhosis: Implications for Drug Dosage Adjustment

Published:2021-08-24 Issue:9 Volume:18 Page:3563-3577
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

El-Khateeb Eman¹²^ORCID,Achour Brahim¹^ORCID,Al-Majdoub Zubida M.¹^ORCID,Barber Jill¹,Rostami-Hodjegan Amin¹³

Affiliation:

1. Centre for Applied Pharmacokinetic Research, University of Manchester, Manchester M13 9PT, U.K.

2. Clinical Pharmacy Department, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt

3. Certara UK Ltd. (Simcyp Division), Sheffield S1 2BJ, U.K.

Funder

Egyptian Government

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.1c00462

Reference62 articles.

1. The burden of liver disease in Europe: A review of available epidemiological data

2. Liver cirrhosis mortality in 187 countries between 1980 and 2010: a systematic analysis

3. Liver fibrosis

4. A Semi-Mechanistic Model to Predict the Effects of Liver Cirrhosis on Drug Clearance

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