Investigation of Spatial Heterogeneity of Salt Disproportionation in Tablets by Synchrotron X-ray Diffractometry-Reference-Cited by-同舟云学术

Investigation of Spatial Heterogeneity of Salt Disproportionation in Tablets by Synchrotron X-ray Diffractometry

Published:2017-03-02 Issue:4 Volume:14 Page:1133-1144
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Koranne Sampada¹^ORCID,Govindarajan Ramprakash²,Suryanarayanan Raj¹^ORCID

Affiliation:

1. Department of Pharmaceutics, College of Pharmacy, University of Minnesota, 9-177 WDH, 308 Harvard Street S.E., Minneapolis, Minnesota 55455, United States

2. Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, S215 PHAR, 115 S. Grand Avenue, Iowa City, Iowa 52242-1112, United States

Funder

William and Mildred Peters Endowment Fund

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.6b01052

Reference42 articles.

1. Salt selection for basic drugs

2. Trends in Active Pharmaceutical Ingredient Salt Selection based on Analysis of the Orange Book Database

3. Disproportionation of the calcium salt of atorvastatin in the presence of acidic excipients

4. Disproportionation of a crystalline citrate salt of a developmental pharmaceutical compound: Characterization of the kinetics using pH monitoring and online Raman spectroscopy plus quantitation of the crystalline free base form in binary physical mixtures using FT-Raman, XRPD and DSC

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