Reduced Toxicity of Liposomal Nitrogen Mustard Prodrug Formulation Activated by an Intracellular ROS Feedback Mechanism in Hematological Neoplasm Models-Reference-Cited by-同舟云学术

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Reduced Toxicity of Liposomal Nitrogen Mustard Prodrug Formulation Activated by an Intracellular ROS Feedback Mechanism in Hematological Neoplasm Models

Published:2019-12-27 Issue: Volume: Page:
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Lin Mengting,Guo Wangwei,Zhang Zhentao,Zhou Yi,Chen Jiejian,Wang Tiantian,Zhong Xincheng,Lu Yiying,Yang Qiyao,Wei Qichun,Han Min^ORCID,Xu Donghang,Gao Jianqing^ORCID

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Zhejiang Medical and Health Science and Technology Plan Project

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.9b00928

Reference30 articles.

1. Therapeutic Potential of Nitrogen Mustard Based Hybrid Molecules

2. Sulfur Mustard Analog Mechlorethamine (Bis(2-chloroethyl)methylamine) Modulates Cell Cycle Progression via the DNA Damage Response in Human Lung Epithelial A549 Cells

3. A Selective Mitochondrial-Targeted Chlorambucil with Remarkable Cytotoxicity in Breast and Pancreatic Cancers

4. Integrated block copolymer prodrug nanoparticles for combination of tumor oxidative stress amplification and ROS-responsive drug release

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4. Novel Terpyridine Conjugated Nitrogen Mustard Derivatives: Synthesis, Spectral Properties, and Anticancer Activity;Russian Journal of General Chemistry;2022-04

5. Redox Control in Acute Lymphoblastic Leukemia: From Physiology to Pathology and Therapeutic Opportunities;Cells;2021-05-17

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