Increasing the Net Negative Charge by Replacement of DOTA Chelator with DOTAGA Improves the Biodistribution of Radiolabeled Second-Generation Synthetic Affibody Molecules-Reference-Cited by-同舟云学术

Increasing the Net Negative Charge by Replacement of DOTA Chelator with DOTAGA Improves the Biodistribution of Radiolabeled Second-Generation Synthetic Affibody Molecules

Published:2016-04-06 Issue:5 Volume:13 Page:1668-1678
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Westerlund Kristina¹,Honarvar Hadis²,Norrström Emily¹,Strand Joanna²,Mitran Bogdan³,Orlova Anna³,Eriksson Karlström Amelie¹,Tolmachev Vladimir²

Affiliation:

1. Division of Protein Technology, School of Biotechnology, KTH Royal Institute of Technology, AlbaNova University Center, 106 91 Stockholm, Sweden

2. Institute for Immunology, Genetics and Pathology, Uppsala University, 751 05 Uppsala, Sweden

3. Preclinical PET Platform, Department of Medicinal Chemistry, Uppsala University, 751 05 Uppsala, Sweden

Funder

Vetenskapsrådet

Cancerfonden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.6b00089

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4. Influence of Labelling Methods on Biodistribution and Imaging Properties of Radiolabelled Peptides for Visualisation of Molecular Therapeutic Targets

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